Age Range: 18-80
Gender: Any
Study Description: This study is testing an investigational injectable medication for the treatment of Non-Alcoholic Steatohepatitis (NASH), newly known as Metabolic Dysfunction Associated Steatohepatitis (MASH) and Fibrosis. Participants will receive either the study medication or a placebo as an injection, either weekly or bi-weekly, for 3 years. Additional procedures and tests will include vital signs, physical exams, laboratory tests, liver biopsies, FibroScans®and electrocardiograms (ECGs). Total participation will last approximately 3 years and 4 months, including 14 doctor’s visits and 4 phone visits throughout the study. Eligibility for the study will be determined by the study doctor following completion of all screening tests and procedures at an in-person screening visit to the clinic. Trial-related procedures and study medication will be provided at no cost.
Qualifications:
- Must be in stage 2, 3, or 4 Fibrosis
- Cannot have experienced significant weight gain or weight loss in the last 3 months (5% of body weight)
Qualifications:
- Cannot be diagnosed with asthma, lung fibrosis, pulmonary hypertension, interstitial lung disease, or sarcoidosis
PROOF REQUIRED
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